Dr McDowell is an experienced academic and has published widely in Cardiology and Clinical Pathology. In addition to research papers, in peer reviewed medical journals, Dr McDowell has published chapters in research focused-, undergraduate- and postgraduate biomedical and clinical science textbooks. His research publications focus on the development and validation of novel biomarkers for acute coronary syndromes and heart failure. His research interests and approach to research with impact is underpinned by his clinical background in Clinical Biochemistry.
Recent Publications
Examples of recent publications may be found below:
Embryo morphokinetics are subtly affected by patient and treatment parameters exhibiting complex relationships rather than a systemic effect, as analysed using multiple regression on 2376 embryos from 639 patients.
The rapid turnaround time of point of care (POC) cardiac troponin (cTn) assays is highly attractive for crowded Emergency Departments (EDs). We evaluated the diagnostic accuracy of the Troponin-only Manchester Acute Coronary Syndromes (T-MACS) decision aid with a POC cTn assay.
Slevin, M., Lemma, R.S., Zeinolabediny, Y., Liu, D., Ferris, G.R., Caprio, V., Phillips, N., Di Napoli, M., Guo, B., Zeng, X., AlBaradie, R., Binsaleh, N.K., McDowell, G. & Fang, W-H. (2018) Acetylcholine inhibits monomeric C-Reactive Protein inducd inflammation, endothelial cell adhesion and platelet aggregation; A potential therapeutic. Frontiers in Immunology 9 article 2124
Objectives:In this study, we examined the possibility of using targeted antibodies and the potential of small molecular therapeutics (acetylcholine, nicotine and tacrine) to block the pro-inflammatory and adhesion-related properties of monomeric C-reactive protein (mCRP).