McDowell, G. (2016) ‘Thyroid Disease’. In: Admed, N. (ed) (2016) Fundamentals of Biomedical Science Clinical Biochemistry. 2nd Edition. Oxford University Press. pp 284-299. (16 pages)
Learning objectives
After studying this chapter you should be able to:
- Describe the structure and function of the thyroid gland
- Explain the function of thyroid hormones
- Outline the action of thyroid hormones and control of their secretion from the thyroid gland
- Describe the conditions which lead to abnormal thyroid hormone production
- Discuss the investigation of suspected thyroid dysfunction
Introduction
The thyroid gland secretes thyroid hormones that are required for normal metabolism of body cells. Disorders of thyroid function can result in either inadequate or excess production of thyroid hormones causing altered cellular metabolism and development of associated clinical features.
This chapter will describe the nature and role of thyroid hormones, their regulation in the blood and the consequences of changes in their secretion. The value of laboratory investigations in diagnosis and monitoring of treatment will be discussed.
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