Research Papers

Body, R., McDowell, G., Carley, S., Ferguson, J. & Mackway-Jones, K. (2010) ‘Diagnosing acute myocardial infarction with troponins: how low can you go?’ Emerg Med J. 27 pp. 292-296.

Body, R., Carley, S., Wibberley, C., McDowell, G., Ferguson, J. & Mackway- Jones, K. (2010) ‘The value of symptoms and signs in the emergent diagnosis of acute coronary syndromes.’ Resuscitation 81 pp. 281-286.

Body, R., Pemberton, P., Ali, F., McDowell, G., Carley, S., Smith, A. & Mackway-Jones, K. (2011) ‘Low soluble P-selectin may facilitate early exclusion of acute myocardial infarction.’ Clin Chem Acta 412 pp. 614-618.

McDowell, G., Slevin, M. & Krupinski, J. (2011) ‘Nanotechnology for treatment of coronary instent restenosis.’ Vascular Cell 3: 8.

Body, R., McDowell, G., Carley, S., Wibberley, C., Ferguson, J. & Mackway-Jones, K. (2011) ‘A FABP-ulous rule out strategy? Heart fatty acid binding protein and troponin for rapid exclusion of acute myocardial infarction.’ Resuscitation 82 pp. 1041-1046.

Kirwan, C.C., McDowell, G., McCollum, C.N. & Byrne, G.J. (2011) ‘Incidence of venous thromboembolism during chemotherapy for breast cancer: Impact on cancer outcome.’ Anticancer Res 31 pp. 2383-2388.

Body, R., Carley, S., McDowell, G., Jaffe, A.S., France, M., Cruickshank, K., Wibberley, C., Nuttall, M. & Mackway-Jones, K. (2011) ‘Rapid exclusion of acute myocardial infarction in patients’ with undetectable troponin using a high sensitivity assay.’ J Am Coll Cardiol 58 pp. 1332-1339.

Slevin, M., Ahmed, N., Wang, Q., McDowell, G. & Badimon, L. (2012) ‘Unique vascular protective properties of natural products: supplements of future main-line drugs with significant anti-atherosclerotic potential.’ Vascular Cell 4: 9.

Slevin, M., Baldellou, M., Hill, E., Alexander, Y., McDowell, G., Murgatroyd, C., Carroll, M., Degens, H., Krupinski, J., Rovira, N., Chowdhury, M., Serracino-Inglott, F., Badimon, L. (2014). ‘Novel methods for accurate identification, isolation, and genomic analysis of symptomatic microenvironments in atherosclerotic arteries.’ Methods Mol Biol 1135 pp. 289-305.

Body, R., Carley, S., McDowell, G., Pemberton, P., Burrows, G., Cook, G., Lewis, P.S., Smith, A., Mackway-Jones, K. (2014) ‘The Manchester Acute Coronary Syndromes (MACS) decision rule for suspected cardiac chest pain: derivation and external validation.’ Heart 100 pp. 1462-1468.

Kirwan, C.C., McCollum, C.N., McDowell, G. & Byrne, G.J. (2015) ‘Investigation of proposed mechanisms of chemotherapy-induced venous thromboembolism: Endothelial cell activation and pro-coagulant release due to apoptosis. Clinical and Applied Thrombosis and Haemostasis 21 pp. 420-427.

Body, R., Carlton, E., Sperrin, M., Lewis, P.S., Burrows, G., Carley, S., McDowell, G., Buchan, I., Greaves, K. & Mackway-Jones, K. (2017). Troponin only Manchester Acute Coronary Syndromes (T-MACS) decision aid: single biomarker re-derivation and external validation in three cohorts. Emerg Med J 34 pp. 349-356

Mashali, M., Norris, N., McDowell, G. & Body, R. (2016) The inter-observer reliability of a novel qualitative point of care assay for heart-type fatty acid binding protein. Clin Biochem 49 pp. 1199-1201

Barrie, A., Homberg, R., McDowell, G., Brown, J., Kingsland, C., Troup, S. (2017) Embryos cultured in a time lapse system result in superior treatment outcomes: A strict matched pair analysis. Human Fertility 20 pp. 179-185.

Fang, W-H., Kumar, S., McDowell, G., Smith, D., Krupinski, J., Olah, P., Al-Baradie, R., Al-Rukban, M.O., Petcu, E.B. & Slevin M. (2016) Mesenchymal stem cells loaded with p5, derived from CDK5 Activator p35, inhibit calcium-induced CDK5 activation in endothelial cells. Stem Cells International doi.org/10.1155/2016/2165462.

Body, R. & McDowell, G. (2017) The rise and fall of cardiac troponin T. Clinical Chemistry 63 pp. 437

Barrie, A., Homberg, R., McDowell, G., Brown, J., Kingsland, C. & Troup, S. (2017) Examining the efficacy of six published time-lapsed imaging embryo selection algorithms to predict implantation to demonstrate the need for development of specific, in-house morphokinetic selection algorithms. Fert Steril 107 pp. 613-621

Barrie, A., Homberg, R., McDowell, G., Brown, J., Kingsland, C. & Troup, S. (2017) Preliminary investigation of the prevalence and implantation potential of abnormal embryonic phenotype assessed using time-lapse imaging. Reprod Biomed Online 34 pp. 455-462.

Slevin, M., Lemma, R.S., Zeinolabediny, Y., Liu, D., Ferris, G.R., Caprio, V., Phillips, N., Di Napoli, M., Guo, B., Zeng, X., AlBaradie, R., Binsaleh, N.K., McDowell, G. & Fang, W-H. (2018) Acetylcholine inhibits monomeric C-Reactive Protein inducd inflammation, endothelial cell adhesion and platelet aggregation; A potential therapeutic. Frontiers in Immunology 9 article 2124

Body, R., Almashali, M., Morris, N., Moss, P., Jarmin. H., Appelboam, A., Parris, R., Chan, L., Walker, A., Harrison, M., Wooten, A. & McDowell, G. (2019) Diagnostic accuracy of the T-MACS decision aid with a contemporary point of care troponin assay. Heart doi: 10.1136/heartjnl-2018-313825.[epub ahead of print]

Body, R., Twerenbold, R., Austin, C., Boeffinghaus, J., Almashali, M., Nestleberger, T., Norris, N., Badertscher, P., McDowell, G., Wild, K., Moss, P., Rubini Gimenez, M., Jarmen, H., Bigler, N., Einemann, R., Pourmahram, G., Todd, J., Mueller, C., Freemont, A. (2019) Diagnostic accuracy of a high sensitivity cardiac troponin assay with a single serum test in the emergency department. Clinical Chemistry 65 pp. 1006-1014.

Barrie, A., McDowell, G., Troup, S. (2021) An investigation into the effect of potential confounding patient and treatment parameters on human embryo morphokinetics. Fertil Steril doi: 10.1016/j.fertnstert.2020.10.03. [epub ahead of print].