{"id":99,"date":"2017-12-17T15:56:58","date_gmt":"2017-12-17T15:56:58","guid":{"rendered":"http:\/\/clinicalbiochemistry.net\/?page_id=99"},"modified":"2022-08-24T08:55:47","modified_gmt":"2022-08-24T08:55:47","slug":"projects","status":"publish","type":"page","link":"http:\/\/clinicalbiochemistry.net\/?page_id=99","title":{"rendered":"Projects"},"content":{"rendered":"<p><img data-attachment-id=\"55\" data-permalink=\"http:\/\/clinicalbiochemistry.net\/?attachment_id=55\" data-orig-file=\"https:\/\/i0.wp.com\/clinicalbiochemistry.net\/wp-content\/uploads\/2017\/12\/Analyser-Pages.png?fit=800%2C533\" data-orig-size=\"800,533\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"Analyser &#8211; Pages\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/clinicalbiochemistry.net\/wp-content\/uploads\/2017\/12\/Analyser-Pages.png?fit=300%2C200\" data-large-file=\"https:\/\/i0.wp.com\/clinicalbiochemistry.net\/wp-content\/uploads\/2017\/12\/Analyser-Pages.png?fit=750%2C500\" loading=\"lazy\" class=\"size-medium wp-image-55 alignleft\" src=\"https:\/\/i0.wp.com\/clinicalbiochemistry.net\/wp-content\/uploads\/2017\/12\/Analyser-Pages.png?resize=300%2C200\" alt=\"\" width=\"300\" height=\"200\" srcset=\"https:\/\/i0.wp.com\/clinicalbiochemistry.net\/wp-content\/uploads\/2017\/12\/Analyser-Pages.png?resize=300%2C200 300w, https:\/\/i0.wp.com\/clinicalbiochemistry.net\/wp-content\/uploads\/2017\/12\/Analyser-Pages.png?resize=768%2C512 768w, https:\/\/i0.wp.com\/clinicalbiochemistry.net\/wp-content\/uploads\/2017\/12\/Analyser-Pages.png?w=800 800w\" sizes=\"(max-width: 300px) 100vw, 300px\" data-recalc-dims=\"1\" \/>Details of Current and future projects my be found below.<\/p>\n<ol>\n<li><span style=\"color: #39559c;\">Research underpins specific clinical objectives such as:<\/span><\/li>\n<li><span style=\"color: #39559c; font-size: 16px;\">Generating and validating accurate and timely diagnostics for acute coronary syndromes<\/span><\/li>\n<li><span style=\"color: #39559c; font-size: 16px;\">Improved diagnosis of acute coronary syndromes and heart failure<\/span><\/li>\n<li><span style=\"color: #39559c; font-size: 16px;\">Better management of heart failure, through improved understanding of the underlying patho-physiology<\/span><\/li>\n<li><span style=\"color: #39559c; font-size: 16px;\">Improved understanding of the prognostic roles of cardiac biomarkers<\/span><\/li>\n<\/ol>\n\n\n<a class=\"maxbutton-32 maxbutton maxbutton-phd-studentships\" target=\"_blank\" title=\"PhD Studentships\" rel=\"noopener\" href=\"http:\/\/clinicalbiochemistry.net\/?page_id=519\"><span class='mb-text'>PhD Studentships<\/span><\/a>\n\n\n<a class=\"maxbutton-12 maxbutton maxbutton-evamacs\" target=\"_blank\" title=\"Link to Project\" rel=\"noopener\" href=\"http:\/\/clinicalbiochemistry.net\/?page_id=539\"><span class='mb-text'>EVaMACS Study<\/span><\/a>\n\n<a class=\"maxbutton-21 maxbutton maxbutton-macs-t-macs-rule\" target=\"_blank\" title=\"Link to Project\" rel=\"noopener\" href=\"http:\/\/clinicalbiochemistry.net\/?page_id=531\"><span class='mb-text'>MACS &amp; T-MACS Rule<\/span><\/a>\n\n<a class=\"maxbutton-10 maxbutton maxbutton-best-study-project-page\" target=\"_blank\" title=\"BEST Study Project Page\" rel=\"noopener\" href=\"http:\/\/clinicalbiochemistry.net\/?page_id=506\"><span class='mb-text'>BEST Study<\/span><\/a>\n\n\n\n\n<p><\/p>\n\n\n<a class=\"maxbutton-26 maxbutton maxbutton-evidence-synthesis\" title=\"Link to Project\" href=\"\/?page_id=672\"><span class='mb-text'>Evidence Synthesis<\/span><\/a>\n\n\n\n<a class=\"maxbutton-28 maxbutton maxbutton-embryo-selection\" target=\"_blank\" title=\"Embryo Selection\" rel=\"noopener\" href=\"http:\/\/clinicalbiochemistry.net\/?page_id=835\"><span class='mb-text'>Embryo Selection<\/span><\/a>\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Details of Current and future projects my be found below. Research underpins specific clinical objectives such as: Generating and validating accurate and timely diagnostics for acute coronary syndromes Improved diagnosis of acute coronary syndromes and heart failure Better management of<\/p>\n","protected":false},"author":1,"featured_media":227,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"jetpack_post_was_ever_published":false,"_links_to":"","_links_to_target":""},"jetpack_shortlink":"https:\/\/wp.me\/P9tPlw-1B","jetpack-related-posts":[{"id":51,"url":"http:\/\/clinicalbiochemistry.net\/?page_id=51","url_meta":{"origin":99,"position":0},"title":"Research","date":"December 17, 2017","format":false,"excerpt":"Dr McDowell's research interest is focused on the translational aspects of the\u00a0development and clinical validation of biomarkers for diagnostic and\/or prognostic testing in cardiology, heart failure and oncology,\u00a0supported by developing an understanding of the pathophysiology of disease. Research underpins specific clinical objectives: \u00a0 \u00a0 Generating and validating accurate and timely\u2026","rel":"","context":"Similar post","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":568,"url":"http:\/\/clinicalbiochemistry.net\/?page_id=568","url_meta":{"origin":99,"position":1},"title":"T-MACS and POCT Troponin","date":"January 17, 2019","format":false,"excerpt":"The Troponin-only Manchester Acute Coronary Syndromes (T-MACS) decision aid for rapid rule-in and rule-out of acute coronary syndromes using a contemporary point of care troponin assay Richard Body; Malak Almashali; Niall Morris; Phil Moss; Heather Jarman; Andrew Appelboam; Richard Parris; Louisa Chan; Alison Walker; Mark Harrison; Andrea Wootten; Garry McDowellc\u2026","rel":"","context":"Similar post","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":539,"url":"http:\/\/clinicalbiochemistry.net\/?page_id=539","url_meta":{"origin":99,"position":2},"title":"Early Vascular Markers of Acute Coronary Syndromes.","date":"January 11, 2019","format":false,"excerpt":"Purpose: To study the utility of incorporating early vascular activation markers into a clinical decision rule to risk stratify patients according to their risk of a significant myocardial event. Methods:\u00a0We recruited a cohort of patients with symptoms suggest of\u00a0\u00a0ACS presenting to the emergency department. Blood was obtained to determine if\u2026","rel":"","context":"Similar post","img":{"alt_text":"","src":"https:\/\/i0.wp.com\/clinicalbiochemistry.net\/wp-content\/uploads\/2017\/12\/Cardiac-Marker-Test-Pages.png?resize=350%2C200","width":350,"height":200},"classes":[]},{"id":49,"url":"http:\/\/clinicalbiochemistry.net\/?page_id=49","url_meta":{"origin":99,"position":3},"title":"Research Expertise","date":"December 17, 2017","format":false,"excerpt":"\u00a0 Research Expertise Cardiology Cardiovascular Disease Acute Cardiology Acute Coronary Syndromes Diagnostics Heart Failure Diagnostics Heart Failure Physiology and Patho-physiology Angiogenesis Cardiac Biomarkers Diagnostic and Prognostic role of Cardiac Biomarkers Methodological Knowledge Immunoassay Point of Care Testing (Near Patient Testing) Cell Biology Clinical Trials Diagnostic Studies Cohort Studies Biomarker development\u2026","rel":"","context":"Similar post","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":403,"url":"http:\/\/clinicalbiochemistry.net\/?page_id=403","url_meta":{"origin":99,"position":4},"title":"Portfolio","date":"December 23, 2018","format":false,"excerpt":"Dr McDowell is an experienced academic and has published widely in Cardiology and Clinical Pathology. In addition to research papers, in peer reviewed medical journals, Dr McDowell has published chapters in research focused-, undergraduate- and postgraduate biomedical and clinical science textbooks. His research publications focus on the development and validation\u2026","rel":"","context":"Similar post","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":659,"url":"http:\/\/clinicalbiochemistry.net\/?page_id=659","url_meta":{"origin":99,"position":5},"title":"MACS Rule","date":"February 7, 2019","format":false,"excerpt":"Body, R., Carley, S.,\u00a0McDowell, G., Pemberton, P., Burrows, G., Cook, G., Lewis, P.S., Smith, A., Mackway-Jones, K. (2014) \u2018The Manchester Acute Coronary Syndromes (MACS) decision rule for suspected cardiac chest pain: derivation and external validation.\u2019 Heart 100 pp. 1462-1468.\u00a0 Objective:We aimed to derive and validate a clinical decision rule (CDR)\u2026","rel":"","context":"Similar post","img":{"alt_text":"","src":"https:\/\/i0.wp.com\/clinicalbiochemistry.net\/wp-content\/uploads\/2019\/01\/MACS-Paper-e1549807711724.png?fit=400%2C331&resize=350%2C200","width":350,"height":200},"classes":[]}],"_links":{"self":[{"href":"http:\/\/clinicalbiochemistry.net\/index.php?rest_route=\/wp\/v2\/pages\/99"}],"collection":[{"href":"http:\/\/clinicalbiochemistry.net\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/clinicalbiochemistry.net\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/clinicalbiochemistry.net\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/clinicalbiochemistry.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=99"}],"version-history":[{"count":17,"href":"http:\/\/clinicalbiochemistry.net\/index.php?rest_route=\/wp\/v2\/pages\/99\/revisions"}],"predecessor-version":[{"id":987,"href":"http:\/\/clinicalbiochemistry.net\/index.php?rest_route=\/wp\/v2\/pages\/99\/revisions\/987"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/clinicalbiochemistry.net\/index.php?rest_route=\/wp\/v2\/media\/227"}],"wp:attachment":[{"href":"http:\/\/clinicalbiochemistry.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=99"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}