{"id":51,"date":"2017-12-17T13:50:24","date_gmt":"2017-12-17T13:50:24","guid":{"rendered":"http:\/\/clinicalbiochemistry.net\/?page_id=51"},"modified":"2022-08-23T13:29:27","modified_gmt":"2022-08-23T13:29:27","slug":"research-overview","status":"publish","type":"page","link":"http:\/\/clinicalbiochemistry.net\/?page_id=51","title":{"rendered":"Research"},"content":{"rendered":"

\"\"<\/p>\n

Dr McDowell’s research interest is focused on the translational aspects of the\u00a0development and clinical validation of biomarkers for diagnostic and\/or prognostic testing in cardiology, heart failure and oncology<\/span><\/strong>,\u00a0supported by developing an understanding of the pathophysiology of disease.<\/p>\n

Research underpins specific clinical objectives:<\/p>\n

\u00a0<\/p>\n

\u00a0<\/p>\n

    \n
  1. Generating and validating accurate and timely diagnostics for acute coronary syndroms<\/strong><\/span><\/li>\n
  2. Improved diagnosis of acute coronary syndromes and heart failure<\/strong><\/li>\n
  3. Better management of heart failure, through improved understanding of the underlying patho-physiology<\/strong><\/li>\n
  4. Improved understanding of the prognostic roles of cardiac biomarkers<\/strong><\/li>\n<\/ol>\n

    We have a number of highly successful collaborations with clinicians and scientists who are experts in their respective fields.<\/p>\n

    I am also committed to collaborating and participating in important collaborative studies and have recently contributed to studies in predicting thrombosis in patients undergoing chemotherapy for breast cancer and additionally the therapeutic potential of novel drug delivery mechanisms, in cardiovascular disease and oncology.<\/p>\n

    \"\"<\/p>\n

    Dr McDowell has a over\u00a080 refereed publications<\/span><\/strong>,\u00a0with a further papers in preparation.<\/p>\n

    Publications are in\u00a0high impact factor journals including British Journal of Cancer, Resuscitation, Heart and Journal of American College of Cardiology<\/em><\/strong><\/span>.<\/span><\/p>\n\n\n

    <\/p>\n\n\nExpertise<\/span><\/a>\n\nProjects<\/span><\/a>","protected":false},"excerpt":{"rendered":"

    Dr McDowell’s research interest is focused on the translational aspects of the\u00a0development and clinical validation of biomarkers for diagnostic and\/or prognostic testing in cardiology, heart failure and oncology,\u00a0supported by developing an understanding of the pathophysiology of disease. Research underpins specific<\/p>\n","protected":false},"author":1,"featured_media":200,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"jetpack_post_was_ever_published":false,"_links_to":"","_links_to_target":""},"jetpack_shortlink":"https:\/\/wp.me\/P9tPlw-P","jetpack-related-posts":[{"id":99,"url":"http:\/\/clinicalbiochemistry.net\/?page_id=99","url_meta":{"origin":51,"position":0},"title":"Projects","date":"December 17, 2017","format":false,"excerpt":"Details of Current and future projects my be found below. Research underpins specific clinical objectives such as: Generating and validating accurate and timely diagnostics for acute coronary syndromes Improved diagnosis of acute coronary syndromes and heart failure Better management of heart failure, through improved understanding of the underlying patho-physiology Improved\u2026","rel":"","context":"Similar post","img":{"alt_text":"","src":"https:\/\/i0.wp.com\/clinicalbiochemistry.net\/wp-content\/uploads\/2017\/12\/Analyser-Pages-300x200.png?resize=350%2C200","width":350,"height":200},"classes":[]},{"id":49,"url":"http:\/\/clinicalbiochemistry.net\/?page_id=49","url_meta":{"origin":51,"position":1},"title":"Research Expertise","date":"December 17, 2017","format":false,"excerpt":"\u00a0 Research Expertise Cardiology Cardiovascular Disease Acute Cardiology Acute Coronary Syndromes Diagnostics Heart Failure Diagnostics Heart Failure Physiology and Patho-physiology Angiogenesis Cardiac Biomarkers Diagnostic and Prognostic role of Cardiac Biomarkers Methodological Knowledge Immunoassay Point of Care Testing (Near Patient Testing) Cell Biology Clinical Trials Diagnostic Studies Cohort Studies Biomarker development\u2026","rel":"","context":"Similar post","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":403,"url":"http:\/\/clinicalbiochemistry.net\/?page_id=403","url_meta":{"origin":51,"position":2},"title":"Portfolio","date":"December 23, 2018","format":false,"excerpt":"Dr McDowell is an experienced academic and has published widely in Cardiology and Clinical Pathology. In addition to research papers, in peer reviewed medical journals, Dr McDowell has published chapters in research focused-, undergraduate- and postgraduate biomedical and clinical science textbooks. His research publications focus on the development and validation\u2026","rel":"","context":"Similar post","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":65,"url":"http:\/\/clinicalbiochemistry.net\/?page_id=65","url_meta":{"origin":51,"position":3},"title":"Publications","date":"December 17, 2017","format":false,"excerpt":"Dr McDowell is an experienced academic and has published widely in Cardiology and Clinical Pathology. In addition to research papers, in peer reviewed medical journals, Dr McDowell has published chapters in research focused-, undergraduate- and postgraduate biomedical and clinical science textbooks. His research publications focus on the development and validation\u2026","rel":"","context":"Similar post","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":629,"url":"http:\/\/clinicalbiochemistry.net\/?page_id=629","url_meta":{"origin":51,"position":4},"title":"Risk Factors and AMI","date":"February 7, 2019","format":false,"excerpt":"Body, R.,\u00a0McDowell, G.,Carley, S. & Mackway-Jones, K. (2008) \u2018Do risk factors for chronic coronary heart disease help diagnose acute myocardial infarction in the emergency department.\u2019\u00a0Resuscitation79 pp. 41-45.\u00a0 Background:Hypertension, hyperlipidaemia, diabetes mellitus, tobacco smoking and a family history of premature coronary artery disease are known to be risk factors for the\u2026","rel":"","context":"Similar post","img":{"alt_text":"","src":"https:\/\/i0.wp.com\/clinicalbiochemistry.net\/wp-content\/uploads\/2019\/01\/Risk-factors-for-ED-diagnosis-e1549807935709.png?fit=400%2C313&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":539,"url":"http:\/\/clinicalbiochemistry.net\/?page_id=539","url_meta":{"origin":51,"position":5},"title":"Early Vascular Markers of Acute Coronary Syndromes.","date":"January 11, 2019","format":false,"excerpt":"Purpose: To study the utility of incorporating early vascular activation markers into a clinical decision rule to risk stratify patients according to their risk of a significant myocardial event. Methods:\u00a0We recruited a cohort of patients with symptoms suggest of\u00a0\u00a0ACS presenting to the emergency department. Blood was obtained to determine if\u2026","rel":"","context":"Similar post","img":{"alt_text":"","src":"https:\/\/i0.wp.com\/clinicalbiochemistry.net\/wp-content\/uploads\/2017\/12\/Cardiac-Marker-Test-Pages.png?resize=350%2C200","width":350,"height":200},"classes":[]}],"_links":{"self":[{"href":"http:\/\/clinicalbiochemistry.net\/index.php?rest_route=\/wp\/v2\/pages\/51"}],"collection":[{"href":"http:\/\/clinicalbiochemistry.net\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/clinicalbiochemistry.net\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/clinicalbiochemistry.net\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/clinicalbiochemistry.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=51"}],"version-history":[{"count":20,"href":"http:\/\/clinicalbiochemistry.net\/index.php?rest_route=\/wp\/v2\/pages\/51\/revisions"}],"predecessor-version":[{"id":948,"href":"http:\/\/clinicalbiochemistry.net\/index.php?rest_route=\/wp\/v2\/pages\/51\/revisions\/948"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/clinicalbiochemistry.net\/index.php?rest_route=\/wp\/v2\/media\/200"}],"wp:attachment":[{"href":"http:\/\/clinicalbiochemistry.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=51"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}