{"id":261,"date":"2017-12-31T10:00:18","date_gmt":"2017-12-31T10:00:18","guid":{"rendered":"http:\/\/clinicalbiochemistry.net\/?page_id=261"},"modified":"2018-12-31T14:32:10","modified_gmt":"2018-12-31T14:32:10","slug":"261-2","status":"publish","type":"page","link":"http:\/\/clinicalbiochemistry.net\/?page_id=261","title":{"rendered":"Time lapse embryo culture"},"content":{"rendered":"

Barrie, A., Homberg, R., McDowell, G<\/strong>., Brown, J., Kingsland, C., Troup, S. (2017) Embryos cultured in a time lapse system result in superior treatment outcomes: A strict matched pair analysis. Human Fertility 20 pp. 179-185.<\/p>\n

\"\"A retrospective, strict matched-pair analysis on 728 treatment cycles between January 2011 and September 2014 was performed. 364 treatment cycles, where all embryos were cultured and examined in EmbryoScope\u00ae, were matched to treatment cycles where all embryos were cultured in a standard incubator with conventional morphological examination. Matching was performed for patient age, number of oocytes collected, treatment type and date of oocyte collection (\u00b1 six months). The clinical (CPR), implantation (IR), live birth (LBR) and miscarriage rates (MR) were calculated and considered significant at p<0.05 (Chi-square test). CPR, IR and LBR were found to be statistically significantly higher in the time-lapse system (TLS) group compared to the standard incubation group (CPR; 44.8% versus 36.5%, p<0.03. IR; 39.3% versus 32.2%, p<0.03. LBR; 43.1% versus 33.8%, p<0.01). Although there was a 5.5% decrease in the MR for the TLS group when compared to the standard incubation group, this result was not statistically significant (18.9% versus 24.4%, p>0.1). There is a paucity of well-designed studies to confirm that embryos cultured and examined in TLS can result in superior treatment outcomes, and this strict-matched pair analysis with a large cohort of treatment cycles indicates the advantage of using TLS.<\/p>\n\nLink to Journal<\/span><\/a>","protected":false},"excerpt":{"rendered":"

Barrie, A., Homberg, R., McDowell, G., Brown, J., Kingsland, C., Troup, S. (2017) Embryos cultured in a time lapse system result in superior treatment outcomes: A strict matched pair analysis. Human Fertility 20 pp. 179-185. A retrospective, strict matched-pair analysis<\/p>\n","protected":false},"author":1,"featured_media":170,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"jetpack_post_was_ever_published":false,"_links_to":"","_links_to_target":""},"jetpack_shortlink":"https:\/\/wp.me\/P9tPlw-4d","jetpack-related-posts":[{"id":255,"url":"http:\/\/clinicalbiochemistry.net\/?page_id=255","url_meta":{"origin":261,"position":0},"title":"Efficacy of Embryo Selection Algorithms","date":"December 31, 2017","format":false,"excerpt":"Barrie, A., Homberg, R., McDowell, G., Brown, J., Kingsland, C. & Troup, S. (2017) Examining the efficacy of six published time-lapsed imaging embryo selection algorithms to predict implantation to demonstrate the need for development of specific, in-house morphokinetic selection algorithms. Fert Steril 107 pp. 613-621 Objective To study the efficacy\u2026","rel":"","context":"Similar post","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":457,"url":"http:\/\/clinicalbiochemistry.net\/?page_id=457","url_meta":{"origin":261,"position":1},"title":"Abnormal Embryonic Developmental Phenotype","date":"December 31, 2018","format":false,"excerpt":"Barrie, A., Homberg, R., McDowell, G., Brown, J., Kingsland, C. & Troup, S. (2017) Preliminary investigation of the prevalence and implantation potential of abnormal embryonic phenotype assessed using time-lapse imaging. Reprod Biomed Online 34 pp. 455-462. 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(2010) \u2018Diagnosing acute myocardial infarction with troponins: how low can you go?\u2019 Emerg Med J. 27 pp. 292-296. Body, R., Carley, S., Wibberley, C., McDowell, G., Ferguson, J. & Mackway- Jones, K. (2010) \u2018The value of symptoms and signs\u2026","rel":"","context":"Similar post","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":549,"url":"http:\/\/clinicalbiochemistry.net\/?page_id=549","url_meta":{"origin":261,"position":4},"title":"PhD Project: BEST Study","date":"January 11, 2019","format":false,"excerpt":"Expediting the confirmation of acute myocardial infarction with point of care troponin and heart fatty acid binding protein testing to facilitate early intervention in emergency department Cardiac troponin is the reference standard biomarker for the diagnosis of acute myocardial infarction (AMI). 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